biocomma® C18 Desalting Purification Cartridges

After synthesis, oligonucleotides are released from solid support by treatment with alkaline solution. The resulting solution contains the anticipated full-length oligonucleotides as well as some failure sequences (error sequences), the amount of which depends on synthesis efficiency. In many applications such as PCR, these failure sequences compete with the full-length sequence, so they must be removed prior to use in order to improve yields of downstream applications.

The C18 desalting purification cartridge is packed with octadecyl (C18) bounded silica gel. The octadecyl groups are very hydrophobic 
and have strong retention for non-polar compounds. Thus DNA molecules can be retained while residual 
salts pass through, endowing you with the power to obtain high-purity DNA products, then use in downstream applications, including PCR and sequencing.
   

Cat.#	Description	Package
DC18150	C18 Desalting Purification Cartridge,50 mg/1 mL	100pcs/box
DC186500-1	C18 Desalting Purification Cartridge,500 mg/6 mL	30pcs/box
DC189650	C18 Desalting Purification Plate,50mg/1mL/96well	4pcs/box
C1896-080	C18 Desalting Purification Plate,80mg/2mL/96well	4pcs/box